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ISLETS OF LANGERHANS
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DeCS
Descriptor
English
:
Islets of Langerhans
Descriptor
Spanish
:
Islotes Pancreáticos
Descriptor
Portuguese
:
Ilhotas Pancreáticas
Synonyms
English
:
Islands of Langerhans
Islet Cells
Nesidioblasts
Pancreas, Endocrine
Pancreatic Islets
Tree Number:
A03.734.414
A06.407.414
Definition
English
:
Irregular microscopic structures consisting of cords of endocrine
cells
that are scattered throughout the
PANCREAS
among the exocrine acini. Each islet is surrounded by
connective tissue
fibers and penetrated by a network of
capillaries
. There are four major cell types. The most abundant beta
cells
(50-80%) secrete
INSULIN
. Alpha
cells
(5-20%) secrete
GLUCAGON
. PP
cells
(10-35%) secrete
PANCREATIC POLYPEPTIDE
.
Delta
cells
(~5%) secrete
SOMATOSTATIN.
Indexing Annotation
English
:
do not confuse with
LANGERHANS CELLS
(skin);
neoplasms
=
ADENOMA
, ISLET CELL or
CARCINOMA
, ISLET CELL or their specifics
Entry Combination - descr/qualif
English
:
Islets of Langerhans
/
transplantation
use
Islets of Langerhans Transplantation
History Note
English
:
91; was ISLANDS OF LANGERHANS 1963-90
Allowable Qualifiers
English
:
abnormalities
anatomy & histology
blood supply
chemistry
cytology
drug effects
embryology
enzymology
growth & development
immunology
injuries
innervation
metabolism
microbiology
pathology
physiology
physiopathology
parasitology
radiography
radiation effects
radionuclide imaging
secretion
surgery
ultrastructure
ultrasonography
virology
Record Number:
29211
Unique Identifier:
D007515
Occurrence in VHL
:
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